In order to further analyze the performance of rubber asphalt, this paper combines the requirements of SHRP system test is considered, using indoor standard test method (JTG E20—2011) to analyze the influencing factors such as rubber powder type, dosage, mixing temperature and matrix asphalt selection. The results show that rubber asphalt is selective for the type and fineness of rubber powder. The coarser the rubber powder is, the better the asphalt performance is, and the softening point of the asphalt is modified by truck tire rubber powder, rutting factor and anti-fatigue factor before and after aging, and the creep stiffness S are better than those of the car tire rubber powder. 16% to 18% of the 20-mesh truck tire rubber powder modified asphalt has 177 ℃ viscosity of 1.7~3.2 Pa·s, and is more suitable for construction needs. As the mixing temperature increases, the high temperature performance and fatigue resistance of the rubber asphalt decrease. It is recommended that the mixing temperature can be controlled within 180 ℃. From the reaction degree of rutting factor and anti-fatigue factor, the higher the asphalt marking is, the lower the asphalt performance index is after rubber powder modification.