To study the influence of various factors on the linear and stress changes of the cable-stayed bridge during closing, taking the closure construction of side span and main span of a wide cable-stayed bridge as the engineering background, the finite element models were established by using the BDCMS software. The influence of cable force, temperature and load on the linearity and stress of the closed bridge is analyzed. The results show that, both temperature and load have a great influence on the linearity and stress of the closed bridge, however the influence on the change of cable force is relatively small. The closure parameters of the side span and main span of the bridge were monitored and analyzed. It can be seen that it is advisable to select 22 o 'clock to 8 o 'clock on the next day as the closing time and the corresponding closing width. The construction accuracy and quality of the bridge can be improved by using this construction scheme, which can provide reference for similar engineering construction.