To broaden the range of asphalt modifiers and improve the existing problems in the present technology, the modified asphalts with different contents were prepared by the NAB and NAP nucleating agents. The basic property, high-temperature rheological property, ultraviolet aging property, long-term pressure aging property, and low-temperature rheological property of nucleating agent modified asphalt were studied by the three index tests, DSR test, ultraviolet aging test, long-term aging test, and BBR test. The results indicate that, the softening point of nucleating agent-modified asphalt increases by 12.73 %, and the penetration decreases by 21.60 %. The nucleating agent modified asphalt shows the good high-temperature rutting resistance. The UV aging indices and long-term aging index of the asphalt with nucleating agent are much lower than those of matrix asphalt, which has significant anti-aging performance. The low-temperature flexibility of nucleating agent-modified asphalt increases, and the low-temperature rheological property is significantly improved. The high-temperature rheology, aging resistance, and low-temperature rheology of matrix asphalt are significantly improved by nucleating agent. The recommended optimum content of nucleating agent is 1.0 % ~ 2.0 %.