In view of the fact that there are few researches on the triaxial shear strength parameters of soil-cement in the existing literature, as well as the cohesion and internal friction angle are crucial to the stability analysis of soil-cement slope, the indoor triaxial shear test is used to analyze the total content, age, confining pressure, fly ash content and their effects on the triaxial shear strength parameters. The results show that the cohesion increases with the increase of age, and the increasing trend is roughly linear. The cohesion at the same age increases with the increase of the total content. In general, the internal friction angle decreases with the increase of age, and the smaller the age, the faster the reduction of the internal friction angle. In general, the greater the total content, the smaller the internal friction angle at the same age. The cohesion increases with the increase of fly ash content, but there is no obvious relationship between internal friction angle and fly ash content. The increment of cohesion and the increment of internal friction angle have less correlation with age. When the total content is small, the increment of cohesion increases with the increase of fly ash content. By contrast, at relatively high total content, the increment of cohesion first increases and then decreases with the increase of fly ash content. The research results of this paper can provide experimental basis for the design and construction of soil-cement in the Pearl River Delta soft soil area.