Typhoon is the key load controlling the large span and tall structures in the coastal areas of China. There is a great difference between typhoon wind profile and conventional good wind profile. Reasonable estimation of typhoon design wind profile is very important to guide the wind resistance design of coastal structures. In this paper, the wind profiles of 8 major standard/standard open landforms at home and abroad were first selected to compare with the measured typhoon profiles. The current norms are difficult to consider the variation characteristics of typhoon profiles with height, and do not include the evolution of typhoon profiles with spatial location. Based on this, three wind profile methods for typhoon design are proposed in this paper, which are: the proposed wind profile based on the specification, the combined wind profile based on the same recurrence period at different heights, and the real wind profile based on the wind speed in the recurrence period at specific heights. Methods 2 and 3 consider the characteristics of the typhoon profile changing with height. The calculated results show that the wind profile obtained by method 2 and method 3 is greater than the standard profile, and the profile obtained by method 2 is close to the mean profile of method 3, but the profile of method 2 May not exist in real typhoons, and the real wind profile of method 3 is nearly half higher than the result of method 2. The wind profile recommended in the current specification may be lower than the actual wind profile of typhoon, and the wind profile based on the 100-year recurrence period at different heights cannot take into account the real profile process of typhoon. If only the static response of wind-induced buildings is considered, the design wind profile of typhoon can be selected according to the outer envelope of Method 3.